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Gertrude Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, and a 1988 recipient of the Nobel Prize in Physiology or Medicine. Working alone as well as with George H. Hitchings, Elion developed a multitude of new drugs, using innovative research methods that would later lead to the development of the AIDS drug AZT.Born in New York City to immigrant parents, she graduated from Hunter College in 1937 and New York University (M.Sc.) in 1941. Unable to obtain a graduate research position due to her gender, she worked as a lab assistant and a high school teacher. Later, she left to work as an assistant to George H. Hitchings at the Burroughs-Wellcome pharmaceutical company (now GlaxoSmithKline). She never obtained a formal Ph.D., but was later awarded an honorary Ph.D from Polytechnic University of New York in 1989 and honorary SD degree from Harvard university in 1998.Rather than relying on trial-and-error, Elion and Hitchings used the differences in biochemistry between normal human cells and pathogens (disease-causing agents) to design drugs that could kill or inhibit the reproduction of particular pathogens without harming the host cells.Elion's inventions include:6-mercaptopurine (Purinethol), the first treatment for leukemia.Azathioprine (Imuran), the first immuno-suppressive agent, used for organ transplants.Allopurinol (Zyloprim), for gout.Pyrimethamine (Daraprim), for malaria.Trimethoprim (Septra), for meningitis, septicemia, and bacterial infections of the urinary and respiratory tracts.Acyclovir (Zovirax), for viral herpes.In 1988 Elion received the Nobel Prize in Medicine, together with Hitchings and Sir James Black. Other awards include the National Medal of Science (1991) and the Lemelson-MIT Lifetime Achievement Award (1997). In 1991 she became the first woman to be inducted into the National Inventors Hall of Fame.In Tom Brokaw's Greatest Generation, there is a chapter devoted to her.Gertrude Elion died in North Carolina in 1999, aged 81. She had moved to the Research Triangle in 1970, and for a time served as a research professor at Duke University. She was unmarried.

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Gertrude B. Elion - Autobiography - Nobelprize.org
Nobelprize.org, The Official Web Site of the Nobel Prize
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1988/elion-autobio.html

Gertrude B. Elion - Wikipedia, the free encyclopedia
Gertrude Elion died in North Carolina in 1999, aged 81. She had moved to the Research Triangle in 1970, and for a time served as a research professor at Duke University.
http://en.wikipedia.org/wiki/Gertrude_B._Elion

Gertrude B. Elion, January 23, 1918—February 21, 1999 | By Mary ...
IN THE SPRING OF 1933 Gertrude Elion graduated from high school and that summer she had to select a major subject before she could begin her freshman year at Hunter ...
http://www.nap.edu/html/biomems/gelion.html

Women of Valor - Gertrude Elion - Overview | Jewish Women's Archive
Overview Gertrude Elion, 1918 – 1999 "It's amazing how much you can accomplish when you don't care who gets the credit." Gertrude Elion's accomplishments over the ...
http://jwa.org/historymakers/elion

Gertrude B. Elion: Biography from Answers.com
There she worked for many years with George Herbert Hitchings, co-recipient with Gertrude Elion of the Nobel Prize in Medicine in 1988. Together, they pioneered ...
http://www.answers.com/topic/gertrude-b-elion

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Number of related websites: 85     Search Bing
+ www.nobelprize.org (2 pages)
+ en.wikipedia.org (2 pages)
+ www.nap.edu (1 page)
+ jwa.org (2 pages)
+ www.answers.com (1 page)
+ www.achievement.org (2 pages)
+ www.wellesley.edu (1 page)
+ inventors.about.com (1 page)
+ www.energyquest.ca.gov (1 page)
+ www.csupomona.edu (1 page)
+ www.encyclopedia.com (2 pages)
+ www.imdb.com (1 page)
+ www.uh.edu (1 page)
+ www.inventionatplay.org (1 page)
+ scienceheroes.com (1 page)
+ nobelprizes.com (1 page)
+ web.mit.edu (2 pages)
+ www.medicinenet.com (1 page)
+ www.chemheritage.org (2 pages)
+ www.famousscientists.org (1 page)
+ www.kids.esdb.bg (1 page)
+ breastcancer.about.com (1 page)
+ www.nytimes.com (1 page)
+ chemistry.about.com (1 page)
+ www.myhero.com (1 page)
+ www.amazon.com (2 pages)
+ answers.encyclopedia.com (1 page)
+ biography.yourdictionary.com (1 page)
+ wiki.answers.com (2 pages)
+ www.amuseum.org (1 page)

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Documents: 60
    [PDF] A Life-saving Team: Gertrude Elion and Dr. George Hitchings
    [PDF] Gertrude B. Elion - Nobel Lecture
    [PDF] Gertrude Belle Elion: Biochemist, Nobel Prize1988⁄
    [PDF] Program and Abstracts
    [PDF] Hitchings-Elion Fellows Follow the Road Less Traveled
    [PDF] Business Set - Advertising
    [PDF] Protein Molecule Modeling
    [PDF] 25th International Conference on Antiviral Research (ICAR ...
    [PDF] Donor Alliance's 25 Years of Living History
    [PDF] Take your students on a journey through the world of
    [PDF] CURRICULUM VITAE
    [PDF] WIN THE NOBEL PRIZE
    [PDF] New Dean to Join College of Nursing in October
    [PDF] Report on the 24th ICAR
    [PDF] Jefferson Medical College Alumni Bulletin Dec.97
    [PDF] Erik De Clercq, M.D. Ph.D.
    [PDF] Great Inventions! (By Women!)
    [PDF] Ocular Antiinfectives
    [PDF] Organ Transplantation: Halfway through the First Century
    [PDF] A Brief History of Great Discoveries in Pharmacology: In ...
    [PDF] AACR
    [PDF] Hoffmann R & Llpacomb W N. ‘Theory
    [PDF] YOUR ESHET CHAYIL NAVIGATOR
    [PDF] Living with Iron (and Oxygen): Questions and Answers about Iron ...
    [PDF] Miracle drug against chronic myeloid leukemia
    [PPT] PowerPoint-Präsentation
    [PPT] Antiviral Drugs: An Overview
    [PPT] Great Inventions & their Inventors
    [PPT] Azathioprin(e)
    [PPT] PREVENÇÃO, CONTROLE E TRATAMENTO DE INFECÇÕES VIRAIS

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